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Titel:

Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.

Dokumenttyp:
Journal Article; Article
Autor(en):
Moosmang, S; Haider, N; Klugbauer, N; Adelsberger, H; Langwieser, N; Muller, J; Stiess, M; Marais, E; Schulla, V; Lacinova, L; Goebbels, S; Nave, KA; Storm, DR; Hofmann, F; Kleppisch, T
Abstract:
Current knowledge about the molecular mechanisms of NMDA receptor (NMDAR)-independent long-term potentiation (LTP) in the hippocampus and its function for memory formation in the behaving animal is limited. NMDAR-independent LTP in the CA1 region is thought to require activity of postsynaptic L-type voltage-dependent Ca2+ channels (Cav1.x), but the underlying channel isoform remains unknown. We evaluated the function of the Cav1.2 L-type Ca2+ channel for spatial learning, synaptic plasticity, an...     »
Zeitschriftentitel:
J Neurosci
Jahr:
2005
Band / Volume:
25
Heft / Issue:
43
Seitenangaben Beitrag:
9883-92
Sprache:
eng
Volltext / DOI:
doi:10.1523/JNEUROSCI.1531-05.2005
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16251435
Print-ISSN:
0270-6474
TUM Einrichtung:
Institut für Neurowissenschaften; Institut für Pharmakologie und Toxikologie
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