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Titel:

Differential regulation of exocytotic fusion and granule-granule fusion in eosinophils by Ca2+ and GTP analogs.

Dokumenttyp:
Journal Article; Article
Autor(en):
Hartmann, J; Scepek, S; Hafez, I; Lindau, M
Abstract:
Dynamics of degranulation was studied in horse eosinophils by patch clamp capacitance measurements. Degranulation was stimulated by intracellular application of calcium, and GTPgammaS or guanosine 5'-(beta,gamma-imido)triphosphate at different concentrations via the patch pipette. Degranulation was quantified by measuring the delay time between the beginning of intracellular perfusion and the first exocytotic event, determining the distribution of time intervals between fusion events and the cap...     »
Zeitschriftentitel:
J Biol Chem
Jahr:
2003
Band / Volume:
278
Heft / Issue:
45
Seitenangaben Beitrag:
44929-34
Sprache:
eng
Volltext / DOI:
doi:10.1074/jbc.M306014200
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12853448
Print-ISSN:
0021-9258
TUM Einrichtung:
Institut für Neurowissenschaften
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