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Title:

Differential regulation of exocytotic fusion and granule-granule fusion in eosinophils by Ca2+ and GTP analogs.

Document type:
Journal Article; Article
Author(s):
Hartmann, J; Scepek, S; Hafez, I; Lindau, M
Abstract:
Dynamics of degranulation was studied in horse eosinophils by patch clamp capacitance measurements. Degranulation was stimulated by intracellular application of calcium, and GTPgammaS or guanosine 5'-(beta,gamma-imido)triphosphate at different concentrations via the patch pipette. Degranulation was quantified by measuring the delay time between the beginning of intracellular perfusion and the first exocytotic event, determining the distribution of time intervals between fusion events and the cap...     »
Journal title abbreviation:
J Biol Chem
Year:
2003
Journal volume:
278
Journal issue:
45
Pages contribution:
44929-34
Language:
eng
Fulltext / DOI:
doi:10.1074/jbc.M306014200
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12853448
Print-ISSN:
0021-9258
TUM Institution:
Institut für Neurowissenschaften
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