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Title:

A randomized, double-blind, placebo-controlled trial on restenosis prevention by the receptor tyrosine kinase inhibitor imatinib.

Document type:
Journal Article; Randomized Controlled Trial; Article
Author(s):
Zohlnhofer, D; Hausleiter, J; Kastrati, A; Mehilli, J; Goos, C; Schuhlen, H; Pache, J; Pogatsa-Murray, G; Heemann, U; Dirschinger, J; Schömig, A
Abstract:
OBJECTIVES: The aim of the present double-blind, placebo-controlled study was to evaluate the efficacy of a systemic imatinib treatment, a potent platelet-derived growth factor (PDGF) receptor kinase inhibitor, for the prevention of recurrent restenosis in patients with in-stent restenosis (ISR). BACKGROUND: Neointima proliferation after stent placement has been associated with the effect of potent mitogenes such as PDGF, and their inhibition has resulted in reduction of neointima formation in e...     »
Journal title abbreviation:
J Am Coll Cardiol
Year:
2005
Journal volume:
46
Journal issue:
11
Pages contribution:
1999-2003
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jacc.2005.07.060
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16325031
Print-ISSN:
0735-1097
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann); I. Medizinische Klinik und Poliklinik (Kardiologie)
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