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Titel:

Polychrome labeling of bone with seven different fluorochromes: enhancing fluorochrome discrimination by spectral image analysis.

Dokumenttyp:
Journal Article; Article
Autor(en):
Pautke, C; Vogt, S; Tischer, T; Wexel, G; Deppe, H; Milz, S; Schieker, M; Kolk, A
Abstract:
Bone formation and remodeling in vivo can be assessed by polychrome labeling using calcium-binding fluorescent dyes. The number of fluorochromes, however, limits this technique due to the fact that with increasing number, fluorescent spectra inevitably overlap, which makes discrimination more difficult. In order to enhance discrimination, we performed spectral image analysis. Non-critical size defects of the femur of male Wistar rats served as a model for bone formation. Eight different fluoroch...     »
Zeitschriftentitel:
Bone
Jahr:
2005
Band / Volume:
37
Heft / Issue:
4
Seitenangaben Beitrag:
441-5
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.bone.2005.05.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16046209
Print-ISSN:
8756-3282
TUM Einrichtung:
Fachgebiet Sportorthopädie (Prof. Imhoff); Institut für Experimentelle Onkologie und Therapieforschung; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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