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Titel:

The urokinase receptor (uPAR, CD87) as a target for tumor therapy: uPA-silica particles (SP-uPA) as a new tool for assessing synthetic peptides to interfere with uPA/uPA-receptor interaction.

Dokumenttyp:
Journal Article; Review
Autor(en):
Guthaus, E; Schmiedeberg, N; Bürgle, M; Magdolen, V; Kessler, H; Schmitt, M
Abstract:
Many different processes in the physiology and pathophysiology of human beings are regulated protein/protein interactions such as receptor/ligand interactions. A more detailed knowledge of the nature of receptor/ligand binding sites and mechanisms of interaction is necessary as well in order to understand the process of cancer spread and metastasis. For instance, the cell surface receptor uPAR (CD87) and its ligand, the serine protease urokinase-type plasminogen activator (uPA), facilitate tumor...     »
Zeitschriftentitel:
Recent Results Cancer Res
Jahr:
2003
Band / Volume:
162
Seitenangaben Beitrag:
3-14
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12790317
Print-ISSN:
0080-0015
TUM Einrichtung:
Frauenklinik und Poliklinik
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