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Title:

Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus.

Document type:
Journal Article; Article
Author(s):
Wegener, JW; Lee, M; Hofmann, F
Abstract:
Thyroid hormones are known to influence various processes of cell differentiation. Recently, it was reported that hypothyroidism reduces the sensitivity to Ca2+-channel antagonists in the rat uterus. We examined the sensitivity to dihydropyridines of the uterus from mice that had reduced thyroid hormone levels. Isradipine relaxed with the same potency precontracted uterine muscle strips from control and hypothyroid mice, independently from a pseudo-pregnant state. These results demonstrate that...     »
Journal title abbreviation:
Can J Physiol Pharmacol
Year:
2003
Journal volume:
81
Journal issue:
9
Pages contribution:
890-3
Language:
eng
Fulltext / DOI:
doi:10.1139/y03-090
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14614526
Print-ISSN:
0008-4212
TUM Institution:
Institut für Pharmakologie und Toxikologie
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