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Titel:

All is not Toll: new pathways in DNA recognition.

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Wagner, H; Bauer, S
Abstract:
Immunological defense depends on the ability of the innate immune system to recognize invading microbes as foreign and thus eliminate them. The Toll-like receptors (TLRs) help detect foreign invaders by sensing various pathogen-associated molecules, including microbial RNA and DNA. At present, it is unclear whether and how the immune system distinguishes between microbial and self nucleic acids, as host-derived RNA and DNA also stimulate TLRs. In addition, recent studies have revealed the existe...     »
Zeitschriftentitel:
J Exp Med
Jahr:
2006
Band / Volume:
203
Heft / Issue:
2
Seitenangaben Beitrag:
265-8
Sprache:
eng
Volltext / DOI:
doi:10.1084/jem.20052191
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16446382
Print-ISSN:
0022-1007
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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