Benutzer: Gast  Login
Weniger Felder
Einfache Suche
Titel:

Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa.

Dokumenttyp:
Journal Article
Autor(en):
Rad, R; Prinz, C; Neu, B; Neuhofer, M; Zeitner, M; Voland, P; Becker, I; Schepp, W; Gerhard, M
Abstract:
Polymorphisms of the IL-1B and IL-1RN genes (which encode interleukin [IL]-1beta and IL-1 receptor antagonist, respectively) have been associated with hypochlorhydria and gastric cancer. We investigated the influence of bacterial virulence factors and host IL-1 polymorphisms on the development of histologic abnormalities in 210 Helicobacter pylori-infected patients with chronic gastritis. cagA(+)/vacAs1(+) H. pylori strains were associated with intestinal metaplasia (IM), atrophic gastritis (AG)...     »
Zeitschriftentitel:
J Infect Dis
Jahr:
2003
Band / Volume:
188
Heft / Issue:
2
Seitenangaben Beitrag:
272-81
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12854083
Print-ISSN:
0022-1899
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
 BibTeX