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Titel:

Contribution of intracolumnar layer 2/3-to-layer 2/3 excitatory connections in shaping the response to whisker deflection in rat barrel cortex.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Sarid, Leora; Feldmeyer, Dirk; Gidon, Albert; Sakmann, Bert; Segev, Idan
Abstract:
This computational study integrates anatomical and physiological data to assess the functional role of the lateral excitatory connections between layer 2/3 (L2/3) pyramidal cells (PCs) in shaping their response during early stages of intracortical processing of a whisker deflection (WD). Based on in vivo and in vitro recordings, and 3D reconstructions of connected pairs of L2/3 PCs, our model predicts that: 1) AMPAR and NMDAR conductances/synapse are 0.52 ± 0.24 and 0.40 ± 0.34 nS, respectively;...     »
Zeitschriftentitel:
Cereb Cortex
Jahr:
2015
Band / Volume:
25
Heft / Issue:
4
Seitenangaben Beitrag:
849-58
Sprache:
eng
Volltext / DOI:
doi:10.1093/cercor/bht268
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24165834
Print-ISSN:
1047-3211
TUM Einrichtung:
Institut für Neurowissenschaften
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