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Title:

Synaptic dynamics and neuronal network connectivity are reflected in the distribution of times in Up states.

Document type:
Journal Article; Article
Author(s):
Dao Duc, Khanh; Parutto, Pierre; Chen, Xiaowei; Epsztein, Jérôme; Konnerth, Arthur; Holcman, David
Abstract:
The dynamics of neuronal networks connected by synaptic dynamics can sustain long periods of depolarization that can last for hundreds of milliseconds such as Up states recorded during sleep or anesthesia. Yet the underlying mechanism driving these periods remain unclear. We show here within a mean-field model that the residence time of the neuronal membrane potential in cortical Up states does not follow a Poissonian law, but presents several peaks. Furthermore, the present modeling approach al...     »
Journal title abbreviation:
Front Comput Neurosci
Year:
2015
Journal volume:
9
Pages contribution:
96
Language:
eng
Fulltext / DOI:
doi:10.3389/fncom.2015.00096
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26283956
TUM Institution:
Institut für Neurowissenschaften
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