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Titel:

Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Price, Philip J R; Banki, Zoltan; Scheideler, Angelika; Stoiber, Heribert; Verschoor, Admar; Sutter, Gerd; Lehmann, Michael H
Abstract:
Efficient leukocyte migration is important for an effective host response to viral infection and the development of adaptive immunity. The poxvirus strain modified vaccinia virus Ankara (MVA), a safe and efficient viral vector, rapidly induces chemokine expression and respiratory recruitment of leukocytes, which is unique among vaccinia viruses. In addition to chemokines, the complement system contributes to the attraction and activation of different types of leukocytes. Using a murine model of...     »
Zeitschriftentitel:
J Immunol
Jahr:
2015
Band / Volume:
194
Heft / Issue:
3
Seitenangaben Beitrag:
1164-8
Sprache:
eng
Volltext / DOI:
doi:10.4049/jimmunol.1301410
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25548218
Print-ISSN:
0022-1767
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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