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Title:

Validation of an IFN?/IL2 FluoroSpot assay for clinical trial monitoring.

Document type:
Journal Article; Article
Author(s):
Körber, Nina; Behrends, Uta; Hapfelmeier, Alexander; Protzer, Ulrike; Bauer, Tanja
Abstract:
The FluoroSpot assay, an advancement of the ELISpot assay, enables simultaneous measurement of different analytes secreted at a single-cell level. This allows parallel detection of several cytokines secreted by immune cells upon antigen recognition. Easier standardization, higher sensitivity and reduced labour intensity render FluoroSpot assays an interesting alternative to flow-cytometry based assays for analysis of clinical samples. While the use of immunoassays to study immunological primary...     »
Journal title abbreviation:
J Transl Med
Year:
2016
Journal volume:
14
Journal issue:
1
Pages contribution:
175
Language:
eng
Fulltext / DOI:
doi:10.1186/s12967-016-0932-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27297580
Print-ISSN:
1479-5876
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Institut für Virologie ; Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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