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Titel:

Toll-like receptor 2 agonist Pam3CSK4 up-regulates Fc?RI receptor expression on monocytes from patients with severe extrinsic atopic dermatitis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Song, Z; Deng, X; Chen, W; Xu, J; Chen, S; Zhong, H; Hao, F
Abstract:
Both microbial antigens and allergens are important factors that can trigger atopic dermatitis (AD). Monocytes from patients with AD have been found to express increased and sustained levels of high-affinity IgE receptor (Fc?RI) and Toll-like receptor 2 (TLR2). We hypothesized that putative interactions exist between TLR2 and Fc?RI on monocytes in the pathogenesis of AD.This study aimed to understand whether activation of TLR2 by Pam3CSK4 would influence the expression of Fc?RI, and whether mito...     »
Zeitschriftentitel:
J Eur Acad Dermatol Venereol
Jahr:
2015
Band / Volume:
29
Heft / Issue:
11
Seitenangaben Beitrag:
2169-76
Sprache:
eng
Volltext / DOI:
doi:10.1111/jdv.13172
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25912722
Print-ISSN:
0926-9959
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie
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