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Titel:

Orexin A attenuates the sleep-promoting effect of adenosine in the lateral hypothalamus of rats.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Cun, Yanping; Tang, Lin; Yan, Jie; He, Chao; Li, Yang; Hu, Zhian; Xia, Jianxia
Abstract:
Orexin neurons within the lateral hypothalamus play a crucial role in the promotion and maintenance of arousal. Studies have strongly suggested that orexin neurons are an important target in endogenous adenosine-regulated sleep homeostasis. Orexin A induces a robust increase in the firing activity of orexin neurons, while adenosine has an inhibitory effect. Whether the excitatory action of orexins in the lateral hypothalamus actually promotes wakefulness and reverses the sleep-producing effect o...     »
Zeitschriftentitel:
Neurosci Bull
Jahr:
2014
Band / Volume:
30
Heft / Issue:
5
Seitenangaben Beitrag:
877-86
Sprache:
eng
Volltext / DOI:
doi:10.1007/s12264-013-1442-8
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24898402
Print-ISSN:
1673-7067
TUM Einrichtung:
Institut für Neurowissenschaften
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