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Title:

Cortical control of adaptation and sensory relay mode in the thalamus.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Mease, Rebecca A; Krieger, Patrik; Groh, Alexander
Abstract:
A major synaptic input to the thalamus originates from neurons in cortical layer 6 (L6); however, the function of this cortico-thalamic pathway during sensory processing is not well understood. In the mouse whisker system, we found that optogenetic stimulation of L6 in vivo results in a mixture of hyperpolarization and depolarization in the thalamic target neurons. The hyperpolarization was transient, and for longer L6 activation (>200 ms), thalamic neurons reached a depolarized resting membran...     »
Journal title abbreviation:
Proc Natl Acad Sci U S A
Year:
2014
Journal volume:
111
Journal issue:
18
Pages contribution:
6798-803
Language:
eng
Fulltext / DOI:
doi:10.1073/pnas.1318665111
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24748112
Print-ISSN:
0027-8424
TUM Institution:
Institut für Neurowissenschaften
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