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Titel:

Regeneration of myelin sheaths of normal length and thickness in the zebrafish CNS correlates with growth of axons in caliber.

Dokumenttyp:
Journal Article; Article
Autor(en):
Karttunen, Marja J; Czopka, Tim; Goedhart, Marieke; Early, Jason J; Lyons, David A
Abstract:
Demyelination is observed in numerous diseases of the central nervous system, including multiple sclerosis (MS). However, the endogenous regenerative process of remyelination can replace myelin lost in disease, and in various animal models. Unfortunately, the process of remyelination often fails, particularly with ageing. Even when remyelination occurs, it is characterised by the regeneration of myelin sheaths that are abnormally thin and short. This imperfect remyelination is likely to have imp...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2017
Band / Volume:
12
Heft / Issue:
5
Seitenangaben Beitrag:
e0178058
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0178058
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28542521
Print-ISSN:
1932-6203
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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