Bonfiglio, Cecilia Assunta;Lacy, Michael;Triantafyllidou, Vasiliki;Farina, Floriana Maria;Janjic, Aleksandar;Nitz, Katrin;Wu, Yuting;Bazioti, Venetia;Avcilar-Kücükgöze, Irem;Marques, Yonara Freire Soares;Joppich, Markus;Kumkum, Mahadia;Röß, Katja;Venkatasubramani, Anuroop Venkateswaran;Imhof, Axel;Enard, Wolfgang;Maegdefessel, Lars;de Winther, Menno;Weber, Christian;Santovito, Donato;Lutgens, Esther;Atzler, Dorothee
Ezh2 Shapes T Cell Plasticity to Drive Atherosclerosis.
Circulation
2025
151
19
1391-1408

Haase, Lara;Belkacemi, Anouar;Neises, Laura;Kiweler, Nicole;Wesely, Christine;Huchzermeier, Rosanna;Bozic, Maja;Khakdan, Arefeh;Sánchez, Marta;Mary, Arnaud;Sachs, Nadja;Winter, Hanna;Glaab, Enrico;Heneka, Michael T;van der Vorst, Emiel Pc;Mittelbronn, Michel;Meiser, Johannes;Schneider, Jochen G
Modulation of the ACOD1/itaconate pathway differentially affects atherosclerosis severity across genetic models and sexes.
J Clin Invest
2025
135
15

Maegdefessel, Lars;Fasolo, Francesca
Long Non-Coding RNA Function in Smooth Muscle Cell Plasticity and Atherosclerosis.
Arterioscler Thromb Vasc Biol
2025
45
2
172-185

Winski, Greg;Chernogubova, Ekaterina;Busch, Albert;Eken, Suzanne M;Jin, Hong;Lindquist Liljeqvist, Moritz;Khan, Tooba;Bäcklund, Alexandra;Paloschi, Valentina;Roy, Joy;Hultgren, Rebecka;Brostjan, Christine;de Borst, Gert J;Sluijter, Joost P G;Sachs, Nadja;Eckstein, Hans-Henning;Boon, Reinier A;Spin, Joshua M;Tsao, Philip S;Asselbergs, Folkert W;Maegdefessel, Lars
MicroRNA-15a-5p mediates abdominal aortic aneurysm progression and serves as a potential diagnostic and prognostic circulating biomarker.
Commun Med (Lond)
2025
5
1

Parma, Laura;Sachs, Nadja;Sobczak, Nikola;Li, Zhaolong;Merchant, Kevin;Pauli, Jessica;Depuydt, Marie A C;Wezel, Anouk;Smeets, Harm J;Bot, Ilze;Slütter, Bram;Maegdefessel, Lars;Weber, Christian;Duchêne, Johan;Megens, Remco T A
CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis.
Circulation
2025
151
8
581-584

Nackenhorst, Maja Carina;Menges, Felix;Bohmann, Bianca;Zschäpitz, David;Bollwein, Christine;Flemming, Sven;Sachs, Nadja;Eilenberg, Wolf;Brostjan, Christine;Neumayer, Christoph;Trenner, Matthias;Ibing, Wiebke;Schelzig, Hubert;Reeps, Christian;Maegdefessel, Lars;Regele, Heinz;Wagenhäuser, Markus Udo;Scholz, Claus Jürgen;Gasser, Thomas Christian;Busch, Albert
Abdominal aortic aneurysm histomorphology shows different inflammatory aspects among patients and is not associated with classic risk factors-the HistAAA study.
Cardiovasc Res
2025
121
11
1767-1777

El Bounkari, Omar;Zan, Chunfang;Yang, Bishan;Ebert, Simon;Wagner, Jonas;Bugar, Elina;Kramer, Naomi;Bourilhon, Priscila;Kontos, Christos;Zarwel, Marlies;Sinitski, Dzmitry;Milic, Jelena;Jansen, Yvonne;Kempf, Wolfgang E;Sachs, Nadja;Maegdefessel, Lars;Ji, Hao;Gokce, Ozgun;Riols, Fabien;Haid, Mark;Gerra, Simona;Hoffmann, Adrian;Brandhofer, Markus;Avdic, Maida;Bucala, Richard;Megens, Remco T A;Willemsen, Nienke;Messerer, Denise;Schulz, Christian;Bartelt, Alexander;Harm, Tobias;Rath, Dominik;Döring, Yvonne;Gawaz, Meinrad;Weber, Christian;Kapurniotu, Aphrodite;Bernhagen, Jürgen
An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis.
Nat Commun
2025
16
1

Northoff, Bernd H;Herbst, Andreas;Wenk, Catharina;Weindl, Lena;Gäbel, Gabor;Brezski, Andre;Zarnack, Kathi;Küpper, Alina;Dimmeler, Stefanie;Moretti, Alessandra;Laugwitz, Karl-Ludwig;Engelhardt, Stefan;Maegdefessel, Lars;Boon, Reinier A;Doppler, Stefanie;Dreßen, Martina;Lahm, Harald;Lange, Rüdiger;Krane, Markus;Krohn, Knut;Kohlmaier, Alexander;Holdt, Lesca M;Teupser, Daniel
Circular RNAs increase during vascular cell differentiation and are biomarkers for vascular disease.
Cardiovasc Res
2025
121
3
405-423

Kontidou, Eftychia;Humoud, Rawan;Chernogubova, Ekaterina;Alvarsson, Michael;Maegdefessel, Lars;Collado, Aida;Pernow, John;Zhou, Zhichao
Red blood cells as potential materials for microRNA biomarker study: overcoming heparin-related challenges.
Am J Physiol Heart Circ Physiol
2024
327
5
H1296-H1302

Bamezai, Sharika;Zhang, Yapei;Kumari, Manisha;Lotfi, Mozhgan;Alsaigh, Tom;Luo, Lingfeng;Kumar, Gayatri Suresh;Wang, Fudi;Ye, Jianqin;Puri, Madhu;Manchanda, Romila;Paluri, Sesha;Adkar, Shaunak S;Kojima, Yoko;Ingelsson, Alice;Bell, Caitlin F;Lopez, Nicolas G;Fu, Changhao;Choi, Ryan B;Miller, Zach;Barrios, Leo;Walsh, Susan;Ahmad, Ferhaan;Maegdefessel, Lars;Smith, Bryan Ronain;Leeper, Nicholas J
Pro-efferocytic nanotherapies reduce vascular inflammation without inducing anemia in a large animal model of atherosclerosis.
Nat Commun
2024
15
1