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- Title:
NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.
- Document type:
- Journal Article; Article
- Author(s):
- Symvoulidis, Panagiotis; Lauri, Antonella; Stefanoiu, Anca; Cappetta, Michele; Schneider, Steffen; Jia, Hongbo; Stelzl, Anja; Koch, Maximilian; Perez, Carlos Cruz; Myklatun, Ahne; Renninger, Sabine; Chmyrov, Andriy; Lasser, Tobias; Wurst, Wolfgang; Ntziachristos, Vasilis; Westmeyer, Gil G
- Abstract:
- A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activ... »
- Journal title abbreviation:
- Nat Methods
- Year:
- 2017
- Journal volume:
- 14
- Journal issue:
- 11
- Pages contribution:
- 1079-1082
- Language:
- eng
- Fulltext / DOI:
- doi:10.1038/nmeth.4459
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/28967889
- Print-ISSN:
- 1548-7091
- TUM Institution:
- Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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