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Title:

Fast histological assessment of adipose tissue inflammation by label-free mid-infrared optoacoustic microscopy.

Document type:
Journal Article
Author(s):
Ko, Vito; Goess, Marie C; Scheel-Platz, Lukas; Yuan, Tao; Chmyrov, Andriy; Jüstel, Dominik; Ruland, Jürgen; Ntziachristos, Vasilis; Keppler, Selina J; Pleitez, Miguel A
Abstract:
Conventional histology, as well as immunohistochemistry or immunofluorescence, enables the study of morphological and phenotypical changes during tissue inflammation with single-cell accuracy. However, although highly specific, such techniques require multiple time-consuming steps to apply exogenous labels, which might result in morphological deviations from native tissue structures. Unlike these techniques, mid-infrared (mid-IR) microspectroscopy is a label-free optical imaging method that retr...     »
Journal title abbreviation:
Npj Imaging
Year:
2023
Journal volume:
1
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s44303-023-00003-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38665236
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland); Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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