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Titel:

Ezetimibe blocks hepatitis B virus infection after virus uptake into hepatocytes.

Dokumenttyp:
Journal Article; Article
Autor(en):
Lucifora, J; Esser, K; Protzer, U
Abstract:
Current treatment of chronic hepatitis B virus (HBV) infection mainly targets viral replication in hepatocytes and leads to curing only in exceptional cases. Despite their potential to improve therapeutic success, no drugs interfering with early infection steps of the hepatotropic pathogen HBV are available to date. Recently, entry of the hepatitis C virus (HCV) has been shown to occur along hepatic cholesterol uptake pathways and ezetimibe, a drug which blocks this lipid transport, has been sho...     »
Zeitschriftentitel:
Antiviral Res
Jahr:
2013
Band / Volume:
97
Heft / Issue:
2
Seitenangaben Beitrag:
195-7
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.antiviral.2012.12.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23266293
Print-ISSN:
0166-3542
TUM Einrichtung:
Institut für Virologie
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