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Title:

Spontaneous persistent activity in entorhinal cortex modulates cortico-hippocampal interaction in vivo.

Document type:
In Vitro; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Hahn, TT; McFarland, JM; Berberich, S; Sakmann, B; Mehta, MR
Abstract:
Persistent activity is thought to mediate working memory during behavior. Can it also occur during sleep? We found that the membrane potential of medial entorhinal cortex layer III (MECIII) neurons, a gateway between neocortex and hippocampus, showed spontaneous, stochastic persistent activity in vivo in mice during Up-Down state oscillations (UDS). This persistent activity was locked to the neocortical Up states with a short delay, but persisted over several cortical UDS cycles. Lateral entorhi...     »
Journal title abbreviation:
Nat Neurosci
Year:
2012
Journal volume:
15
Journal issue:
11
Pages contribution:
1531-8
Language:
eng
Fulltext / DOI:
doi:10.1038/nn.3236
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23042081
Print-ISSN:
1097-6256
TUM Institution:
Institut für Neurowissenschaften
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