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Title:

Kainate receptor-induced retrograde inhibition of glutamatergic transmission in vasopressin neurons.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Bonfardin, VD; Theodosis, DT; Konnerth, A; Oliet, SH
Abstract:
Presynaptic kainate receptors (KARs) exert a modulatory action on transmitter release. We here report that applications of agonists of GluK1-containing KARs in the rat supraoptic nucleus has an opposite action on glutamatergic transmission according to the phenotype of the postsynaptic neuron. Whereas glutamate release was facilitated in oxytocin (OT) neurons, it was inhibited in vasopressin (VP) cells. Interestingly, an antagonist of GluK1-containing KARs caused an inhibition of glutamate relea...     »
Journal title abbreviation:
J Neurosci
Year:
2012
Journal volume:
32
Journal issue:
4
Pages contribution:
1301-10
Language:
eng
Fulltext / DOI:
doi:10.1523/JNEUROSCI.3017-11.2012
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22279215
Print-ISSN:
0270-6474
TUM Institution:
Institut für Neurowissenschaften
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