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Titel:

Spontaneous persistent activity in entorhinal cortex modulates cortico-hippocampal interaction in vivo.

Dokumenttyp:
In Vitro; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Hahn, TT; McFarland, JM; Berberich, S; Sakmann, B; Mehta, MR
Abstract:
Persistent activity is thought to mediate working memory during behavior. Can it also occur during sleep? We found that the membrane potential of medial entorhinal cortex layer III (MECIII) neurons, a gateway between neocortex and hippocampus, showed spontaneous, stochastic persistent activity in vivo in mice during Up-Down state oscillations (UDS). This persistent activity was locked to the neocortical Up states with a short delay, but persisted over several cortical UDS cycles. Lateral entorhi...     »
Zeitschriftentitel:
Nat Neurosci
Jahr:
2012
Band / Volume:
15
Heft / Issue:
11
Seitenangaben Beitrag:
1531-8
Sprache:
eng
Volltext / DOI:
doi:10.1038/nn.3236
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23042081
Print-ISSN:
1097-6256
TUM Einrichtung:
Institut für Neurowissenschaften
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