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Title:

MicroRNAs in the regulation of immune cell functions--implications for atherosclerotic vascular disease.

Document type:
Journal Article; Review
Author(s):
Zernecke, A
Abstract:
Regarded as a chronic inflammatory disease of the vessel wall, the development of atherosclerotic lesions is shaped by immune responses and their regulation. Macrophages and dendritic cells are positioned at the crossroad of innate and adaptive immune responses by sensing atherogenic danger signals and by taking up and presenting antigens. T helper cells and auto-antibodies produced by B cells, together with their cytokine responses in turn modulate atheroprogression. In addition, platelets cont...     »
Journal title abbreviation:
Thromb Haemost
Year:
2012
Journal volume:
107
Journal issue:
4
Pages contribution:
626-33
Language:
eng
Fulltext / DOI:
doi:10.1160/TH11-08-0603
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22318366
Print-ISSN:
0340-6245
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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