User: Guest  Login
Title:

microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans.

Document type:
Journal Article
Author(s):
Bidzhekov, K; Gan, L; Denecke, B; Rostalsky, A; Hristov, M; Koeppel, TA; Zernecke, A; Weber, C
Abstract:
Small non-coding microRNAs (miRNAs) have emerged to play critical roles in cardiovascular biology. Monocytes critically drive atherosclerotic lesion formation, and can be subdivided into a classical and non-classical subset. Here we scrutinised the miRNA signature of human classical and non-classical monocytes, and compared miRNA expression profiles of atherosclerotic plaques from human carotid arteries and healthy arteries. We identified miRNAs to be differentially regulated with a two-fold or...     »
Journal title abbreviation:
Thromb Haemost
Year:
2012
Journal volume:
107
Journal issue:
4
Pages contribution:
619-25
Language:
eng
Fulltext / DOI:
doi:10.1160/TH11-09-0607
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22370758
Print-ISSN:
0340-6245
TUM Institution:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
 BibTeX