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Titel:

Imaging of intact tissue sections: moving beyond the microscope.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
Autor(en):
Seeley, EH; Schwamborn, K; Caprioli, RM
Abstract:
MALDI-imaging MS is a new molecular imaging technology for direct in situ analysis of thin tissue sections. Multiple analytes can be monitored simultaneously without prior knowledge of their identities and without the need for target-specific reagents such as antibodies. Imaging MS provides important insights into biological processes because the native distributions of molecules are minimally disturbed, and histological features remain intact throughout the analysis. A wide variety of molecules...     »
Zeitschriftentitel:
J Biol Chem
Jahr:
2011
Band / Volume:
286
Heft / Issue:
29
Seitenangaben Beitrag:
25459-66
Sprache:
eng
Volltext / DOI:
doi:10.1074/jbc.R111.225854
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21632549
Print-ISSN:
0021-9258
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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