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Title:

Molecular and immunological effects of hyperthermia on tumor progression and metastasis

Document type:
Article
Author(s):
Multhoff, G; Gaipl, U
Abstract:
Hyperthermia treatment in the temperature range 39-43A degrees C can influence the adaptive and natural immune system in addition to the direct toxic effect of temperatures above 41A degrees C on cells. The type of cell destruction (necrosis or apoptosis) plays an important role in whether a pro-inflammatory or anti-inflammatory immune response is triggered by hyperthermia. In addition danger signals, such as high mobility group B1 protein, adenosine-5-triphosphate (ATP) and heat-shock protein,...     »
Journal title abbreviation:
Onkologe
Year:
2010
Journal volume:
16
Journal issue:
11
Pages contribution:
1043-1050
Language:
de
Print-ISSN:
0947-8965
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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