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Titel:

Cartilage tissue engineering for auricular reconstruction: in vitro evaluation of potential genotoxic and cytotoxic effects of scaffold materials.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Havla, JB; Lotz, AS; Richter, E; Froelich, K; Hagen, R; Staudenmaier, R; Kleinsasser, NH
Abstract:
Tissue engineering of autologous cartilage transplants is suggested as a new approach in reconstruction of external auricular deformities. 1.6-Hexanediol (HD), 1.8-diazabicyclo[5.4.0]undec-7-ene (DBU) and 6-hydroxyhexanoic acid (HHA) are matrices of the open-pored polyurethane three-dimensional scaffold. Since these bioresorbable materials may interact with the human organism, cytotoxic effects on human chondrocytes and lymphocytes and genotoxic effects on human lymphocytes were monitored. Stain...     »
Zeitschriftentitel:
Toxicol In Vitro
Jahr:
2010
Band / Volume:
24
Heft / Issue:
3
Seitenangaben Beitrag:
849-53
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.tiv.2009.12.005
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20005288
Print-ISSN:
0887-2333
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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