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Titel:

Tumor endothelial marker 5 expression in endothelial cells during capillary morphogenesis is induced by the small GTPase Rac and mediates contact inhibition of cell proliferation.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Vallon, M; Rohde, F; Janssen, KP; Essler, M
Abstract:
Tumor endothelial marker (TEM) 5 is an adhesion G-protein-coupled receptor upregulated in endothelial cells during tumor and physiologic angiogenesis. So far, the mechanisms leading to upregulation of TEM5 and its function during angiogenesis have not been identified. Here, we report that TEM5 expression in endothelial cells is induced during capillary-like network formation on Matrigel, during capillary morphogenesis in a three-dimensional collagen I matrix, and upon confluence on a two-dimensi...     »
Zeitschriftentitel:
Exp Cell Res
Jahr:
2010
Band / Volume:
316
Heft / Issue:
3
Seitenangaben Beitrag:
412-21
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.yexcr.2009.10.013
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19853600
Print-ISSN:
0014-4827
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin
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