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Document type:
Journal Article
Author(s):
Reissig, Timm M; Uhrig, Sebastian; Jost, Philipp J; Luchini, Claudio; Vicentini, Caterina; Liffers, Sven-Thorsten; Allgäuer, Michael; Adsay, Volkan; Scarpa, Aldo; Lawlor, Rita Teresa; Fröhling, Stefan; Stenzinger, Albrecht; Klöppel, Günter; Schildhaus, Hans-Ulrich; Siveke, Jens T
Title:
MCL1 as putative target in pancreatoblastoma.
Abstract:
Pancreatoblastoma (PB) is a rare tumor of the pancreas. In case of metastases, the treatment options are sparse and targeted approaches are not developed. We here evaluate MCL1 amplification as a putative target in PB.Thirteen samples from adult (10/13) and pediatric patients (3/13) were collected. Three of these samples had been previously subjected to whole-exome sequencing (2 cases) or whole-genome sequencing (1 case) within a precision oncology program (NCT/DKTK MASTER), and this analysis ha...     »
Journal title abbreviation:
Virchows Arch
Year:
2022
Journal volume:
481
Journal issue:
2
Pages contribution:
265-272
Fulltext / DOI:
doi:10.1007/s00428-022-03349-w
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35668118
Print-ISSN:
0945-6317
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie
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