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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Loeb, Rebekka; Navab, Nassir; Ziegler, Sibylle I 
Title:
Direct Parametric Reconstruction Using Anatomical Regularization for Simultaneous PET/MRI Data. 
Abstract:
Pharmacokinetic analysis of dynamic positron emission tomography (PET) imaging data maps the measured time activity curves to a set of model-specific pharmacokinetic parameters. Voxel-based parameter estimation via curve fitting is conventionally performed indirectly on a sequence of independently reconstructed PET images, leading to high variance and bias in the parametric images. We propose a direct parametric reconstruction algorithm with raw projection data as input that leverages high-resol...    »
 
Journal title abbreviation:
IEEE Trans Med Imaging 
Year:
2015 
Journal volume:
34 
Journal issue:
11 
Pages contribution:
2233-47 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0278-0062 
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin