An abdominal aortic aneurysm (AAA) is a frequently asymptomatic ballooning of the aorta, which in case of rupture is terminal for the patient. Experiments on mechanical properties of AAA wall, investigations on biological processes measured by PET images, as well as FE simulations to determine in vivo wall stress were combined to clarify the so far poorly understood mechanobiology during AAA development. Mechanics-based indices were developed, which provide a reliable AAA rupture risk prediction.     «

An abdominal aortic aneurysm (AAA) is a frequently asymptomatic ballooning of the aorta, which in case of rupture is terminal for the patient. Experiments on mechanical properties of AAA wall, investigations on biological processes measured by PET images, as well as FE simulations to determine in vivo wall stress were combined to clarify the so far poorly understood mechanobiology during AAA development. Mechanics-based indices were developed, which provide a reliable AAA rupture risk predictio...     »