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- Title:
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.
- Document type:
- journal article
- Author(s):
- Frank, B; Burwinkel, B; Bermejo, JL; Försti, A; Hemminki, K; Houlston, R; Mangold, E; Rahner, N; Friedl, W; Friedrichs, N; Buettner, R; Engel, C; Loeffler, M; Holinski-Feder, E; Morak, M; Keller, G; Schackert, HK; Krüger, S; Goecke, T; Moeslein, G; Kloor, M; Gebert, J; Kunstmann, E; Schulmann, K; Rüschoff, J; Propping, P; The German HNPCC Consortium
- Abstract:
- Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with colorectal cancer risk in a comprehensive, array based study (AKAP9 M463I, DKK3 G335R, AMPD1 Q12X, LIPC L356F, PSMB9 V32I, THBS1 N700S, CA6 S90G, ASCC3 C1995S, DHX36 S416C and CPA4 G303C) were re-evaluated in the present study based on 626 German familial non-HNPCC colorectal cancer patients and 736 healthy controls. No associations of any of the 10 nsSNPs with colorectal cancer could be replicated.... »
- Journal title abbreviation:
- Cancer Lett
- Year:
- 2008
- Language:
- eng
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/18619730
- Print-ISSN:
- 0304-3835
- TUM Institution:
- Institut für Allgemeine Pathologie und pathologische Anatomie
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