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Title:

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.

Document type:
journal article
Author(s):
Ricketts, Christopher J; De Cubas, Aguirre A; Fan, Huihui; Smith, Christof C; Lang, Martin; Reznik, Ed; Bowlby, Reanne; Gibb, Ewan A; Akbani, Rehan; Beroukhim, Rameen; Bottaro, Donald P; Choueiri, Toni K; Gibbs, Richard A; Godwin, Andrew K; Haake, Scott; Hakimi, A Ari; Henske, Elizabeth P; Hsieh, James J; Ho, Thai H; Kanchi, Rupa S; Krishnan, Bhavani; Kwiatkowski, David J; Lui, Wembin; Merino, Maria J; Mills, Gordon B; Myers, Jerome; Nickerson, Michael L; Reuter, Victor E; Schmidt, Laura S; Shel...     »
Abstract:
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic subtypes, including 488 clear cell RCC, 274 papillary RCC, and 81 chromophobe RCC. Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specifi...     »
Journal title abbreviation:
Cell Rep
Year:
2018
Journal volume:
23
Journal issue:
1
Pages contribution:
313-326.e5
Language:
eng
Fulltext / DOI:
doi:10.1016/j.celrep.2018.03.075
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29617669
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie
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