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Title:

Threshold Analysis and Biodistribution of Fluorescently Labeled Bevacizumab in Human Breast Cancer.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Koch, Maximilian; de Jong, Johannes S; Glatz, Jürgen; Symvoulidis, Panagiotis; Lamberts, Laetitia E; Adams, Arthur L L; Kranendonk, Mariëtte E G; Terwisscha van Scheltinga, Anton G T; Aichler, Michaela; Jansen, Liesbeth; de Vries, Jakob; Lub-de Hooge, Marjolijn N; Schröder, Carolien P; Jorritsma-Smit, Annelies; Linssen, Matthijs D; De Boer, Esther; van der Vegt, Bert; Nagengast, Wouter B; Elias, Sjoerd G; Oliveira, Sabrina; Witkamp, Arjen J; Mali, Willem P T M; Van der Wall, Elsken; Garcia-Allen...     »
Abstract:
In vivo tumor labeling with fluorescent agents may assist endoscopic and surgical guidance for cancer therapy as well as create opportunities to directly observe cancer biology in patients. However, malignant and nonmalignant tissues are usually distinguished on fluorescence images by applying empirically determined fluorescence intensity thresholds. Here, we report the development of fSTREAM, a set of analytic methods designed to streamline the analysis of surgically excised breast tissues by c...     »
Journal title abbreviation:
Cancer Res
Year:
2017
Journal volume:
77
Journal issue:
3
Pages contribution:
623-631
Language:
eng
Fulltext / DOI:
doi:10.1158/0008-5472.CAN-16-1773
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27879266
Print-ISSN:
0008-5472
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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