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Title:

Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Schlitzer, A; Heiseke, AF; Einwächter, H; Reindl, W; Schiemann, M; Manta, CP; See, P; Niess, JH; Suter, T; Ginhoux, F; Krug, AB
Abstract:
The ontogenic relationship between the common dendritic cell (DC) progenitor (CDP), the committed conventional DC precursor (pre-cDC), and cDC subpopulations in lymphoid and nonlymphoid tissues has been largely unraveled. In contrast, the sequential steps of plasmacytoid DC (pDC) development are less defined, and it is unknown at which developmental stage and location final commitment to the pDC lineage occurs. Here we show that CCR9(-) pDCs from murine BM which enter the circulation and periphe...     »
Journal title abbreviation:
Blood
Year:
2012
Journal volume:
119
Journal issue:
25
Pages contribution:
6063-71
Language:
eng
Fulltext / DOI:
doi:10.1182/blood-2012-03-418400
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22547585
Print-ISSN:
0006-4971
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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