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Titel:

miTALOS: Analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs

Autor(en):
Kowarsch, A.; Preusse, M.; Marr, C.; Theis, F. J.
Abstract:
MicroRNAs (miRNAs) are an important class of post-transcriptional regulators of gene expression that are involved in various cellular and phenotypic processes. A number of studies have shown that miRNA expression is induced by signaling pathways. Moreover, miRNAs emerge as regulators of signaling pathways. Here, we present the miTALOS web resource, which provides insight into miRNA-mediated regulation of signaling pathways. As a novel feature, miTALOS considers the tissue-specific expression sig...     »
Stichworte:
microrna signaling pathways computational biology systems biology, prostate cancer cells functional annoation mammalian micrornas protein differenciation activation roles mapk transcriptomes identification
Zeitschriftentitel:
RNA
Jahr:
2011
Band / Volume:
17
Heft / Issue:
5
Seitenangaben Beitrag:
809-819
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