The INFAT-study examines the effect of a reduction in the ratio of n-6/n-3 long-chain polyunsaturated fatty acids in the maternal diet during pregnancy and lactation on adipose tissue development of the infant. The aim of this thesis was to investigate the effect of the dietary intervention on adipokines (leptin, sOB-R, adiponectin) and insulin in maternal blood and breast milk samples during pregnancy and lactation in a subgroup of the INFAT-study. Moreover, these adipokines, insulin and other biomarkers were investigated in cord blood. There was no group effect on maternal and fetal adipokines. Significant correlations between adipokines and blood lipids in the last trimenon were observed. A trend towards lower cord blood insulin concentrations in the intervention group was found.
«
The INFAT-study examines the effect of a reduction in the ratio of n-6/n-3 long-chain polyunsaturated fatty acids in the maternal diet during pregnancy and lactation on adipose tissue development of the infant. The aim of this thesis was to investigate the effect of the dietary intervention on adipokines (leptin, sOB-R, adiponectin) and insulin in maternal blood and breast milk samples during pregnancy and lactation in a subgroup of the INFAT-study. Moreover, these adipokines, insulin and other...
»