Login
- Original title:
- Targeted and non-targeted studies on Alternaria alternata metabolites
- Translated title:
- Targeted und non-targeted Studien zu Metaboliten von Alternaria alternata
- Author:
- Gotthardt, Marina
- Year:
- 2020
- Document type:
- Dissertation
- Faculty/School:
- Fakultät Wissenschaftszentrum Weihenstephan
- Advisor:
- Rychlik, Michael (Prof. Dr.)
- Referee:
- Rychlik, Michael (Prof. Dr.); Engel, Karl-Heinz (Prof. Dr.)
- Language:
- en
- Subject group:
- BIO Biowissenschaften; CHE Chemie
- Keywords:
- Alternaria alternata, fungi, mycotoxins, AOH, AME, ATX I, ALTP, TEN, TA, alterperylenepoxide A 9-mercaptolactate (APML), LC-MS/MS, stable isotope dilution assay (SIDA), infant food, non-targeted, metabolomics, FT-ICR-MS
- Translated keywords:
- Alternaria alternata, Schimmelpilze, Mykotoxine, AOH, AME, ATX I, ALTP, TEN, TA, Alterperylenepoxid A 9-Mercaptolactat (APML), LC-MS/MS, Stabilisotopenverdünnungsanalyse (SIVA), Babynahrung, non-targeted, Metabolomics, FT-ICR-MS
- TUM classification:
- LEB 050d
- Abstract:
- Fungi of the genus Alternaria are widely occurring plant pathogens infecting a multitude of crops, fruits, and vegetables. In the present thesis, a sensitive LC-MS/MS method for the accurate quantification of the Alternaria mycotoxins alternariol, alternariol monomethyl ether, tentoxin, altertoxin I, alterperylenol, and tenuazonic acid in various foods was developed. Besides, non-targeted metabolomics investigations were conducted by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) to obtain deeper insights into the mycobolome of Alternaria fungi.
- Translated abstract:
- Schimmelpilze der Gattung Alternaria sind weit verbreitete Pflanzenpathogene, die eine Vielzahl an Getreide-, Obst- und Gemüsesorten befallen. Die vorliegende Arbeit umfasst die Entwicklung einer sensitiven LC-MS/MS-Methode zur exakten Quantifizierung der Alternaria-Mykotoxine Alternariol, Alternariol-Monomethylether, Tentoxin, Altertoxin I, Alterperylenol und Tenuazonsäure in verschiedenen Lebensmitteln. Um tiefergehende Einblicke in das Metabolom von Alternaria-Pilzen zu erhalten, wurden non-... »
- WWW:
- https://mediatum.ub.tum.de/?id=1543199
- Date of submission:
- 04.05.2020
- Oral examination:
- 26.10.2020
- File size:
- 15290191 bytes
- Pages:
- 201
- Urn (citeable URL):
- https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20201026-1543199-1-7
- Last change:
- 03.12.2020
BibTeX