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Titel:

cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Kleppisch, T; Feil, R
Abstract:
The second messenger cyclic guanosine 3',5'-monophosphate (cGMP) plays a crucial role in the control of cardiovascular and gastrointestinal homeostastis, but its effects on neuronal functions are less established. This review summarizes recent biochemical and functional data on the role of the cGMP signalling pathway in the mammalian brain, with a focus on the regulation of synaptic plasticity, learning, and other complex behaviours. Expression profiling, along with pharmacological and genetic m...     »
Zeitschriftentitel:
Handb Exp Pharmacol
Jahr:
2009
Heft / Issue:
191
Seitenangaben Beitrag:
549-79
Sprache:
eng
Volltext / DOI:
doi:10.1007/978-3-540-68964-5_24
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19089345
Print-ISSN:
0171-2004
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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