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Title:

cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Kleppisch, T; Feil, R
Abstract:
The second messenger cyclic guanosine 3',5'-monophosphate (cGMP) plays a crucial role in the control of cardiovascular and gastrointestinal homeostastis, but its effects on neuronal functions are less established. This review summarizes recent biochemical and functional data on the role of the cGMP signalling pathway in the mammalian brain, with a focus on the regulation of synaptic plasticity, learning, and other complex behaviours. Expression profiling, along with pharmacological and genetic m...     »
Journal title abbreviation:
Handb Exp Pharmacol
Year:
2009
Journal issue:
191
Pages contribution:
549-79
Language:
eng
Fulltext / DOI:
doi:10.1007/978-3-540-68964-5_24
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19089345
Print-ISSN:
0171-2004
TUM Institution:
Institut für Pharmakologie und Toxikologie
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