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Titel:

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

Dokumenttyp:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Intramural; Article
Autor(en):
Milne, RL; Benitez, J; Nevanlinna, H; Heikkinen, T; Aittomäki, K; Blomqvist, C; Arias, JI; Zamora, MP; Burwinkel, B; Bartram, CR; Meindl, A; Schmutzler, RK; Cox, A; Brock, I; Elliott, G; Reed, MW; Southey, MC; Smith, L; Spurdle, AB; Hopper, JL; Couch, FJ; Olson, JE; Wang, X; Fredericksen, Z; Schürmann, P; Bremer, M; Hillemanns, P; Dörk, T; Devilee, P; van Asperen, CJ; Tollenaar, RA; Seynaeve, C; Hall, P; Czene, K; Liu, J; Li, Y; Ahmed, S; Dunning, AM; Maranian, M; Pharoah, PD; Chenevix-Trench, G...     »
Abstract:
BACKGROUND: A recent genome-wide association study identified single-nucleotide polymorphism (SNP) 2q35-rs13387042 as a marker of susceptibility to estrogen receptor (ER)-positive breast cancer. We attempted to confirm this association using the Breast Cancer Association Consortium. METHODS: 2q35-rs13387042 SNP was genotyped for 31 510 women with invasive breast cancer, 1101 women with ductal carcinoma in situ, and 35 969 female control subjects from 25 studies. Odds ratios (ORs) were estimated...     »
Zeitschriftentitel:
J Natl Cancer Inst
Jahr:
2009
Band / Volume:
101
Heft / Issue:
14
Seitenangaben Beitrag:
1012-8
Sprache:
eng
Volltext / DOI:
doi:10.1093/jnci/djp167
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19567422
Print-ISSN:
0027-8874
TUM Einrichtung:
Frauenklinik und Poliklinik
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