Benutzer: Gast  Login
Titel:

Modified vaccinia virus ankara triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Lehmann, MH; Kastenmuller, W; Kandemir, JD; Brandt, F; Suezer, Y; Sutter, G
Abstract:
Orthopoxviruses commonly enter into humans and animals via the respiratory tract. Herein, we show that immigration of leukocytes into the lung is triggered via intranasal infection of mice with modified vaccinia virus Ankara (MVA) and not with the vaccinia virus (VACV) Elstree, Wyeth, or Western Reserve (WR) strain. Immigrating cells were identified as monocytes, neutrophils, and CD4(+) lymphocytes by flow cytometry and could be detected 24 h and 48 h postinfection. Using an in vitro chemotaxis...     »
Zeitschriftentitel:
J Virol
Jahr:
2009
Band / Volume:
83
Heft / Issue:
6
Seitenangaben Beitrag:
2540-52
Sprache:
eng
Volltext / DOI:
doi:10.1128/JVI.01884-08
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19129447
Print-ISSN:
0022-538X
TUM Einrichtung:
Institut für Virologie
 BibTeX