Benutzer: Gast  Login
Titel:

Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Levin, A; Hayouka, Z; Helfer, M; Brack-Werner, R; Friedler, A; Loyter, A
Abstract:
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN), catalyzes the integration of viral DNA into the host cell genome. IN catalyzes the first step of the integration process, namely the 3'-end processing in which IN removes a pGT dinucleotide from the 3' end of each viral long terminal repeat (LTR). Following nuclear import of the viral preintegration complex, the host chromosomal DNA becomes accessible to the viral cDNA and the second step of the integration proce...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2009
Band / Volume:
4
Heft / Issue:
1
Seitenangaben Beitrag:
e4155
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0004155
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19127291
Print-ISSN:
1932-6203
TUM Einrichtung:
Institut für Virologie
 BibTeX