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Titel:

Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Hadian, K; Vincendeau, M; Mäusbacher, N; Nagel, D; Hauck, SM; Ueffing, M; Loyter, A; Werner, T; Wolff, H; Brack-Werner, R
Abstract:
The Rev protein is a key regulator of human immunodeficiency virus type 1 (HIV-1) gene expression. Rev is primarily known as an adaptor protein for nuclear export of HIV RNAs. However, Rev also contributes to numerous other processes by less well known mechanisms. Understanding the functional nature of Rev requires extensive knowledge of its cellular interaction partners. Here we demonstrate that Rev interacts with members of a large family of multifunctional host cell factors called hnRNPs. Rev...     »
Zeitschriftentitel:
J Biol Chem
Jahr:
2009
Band / Volume:
284
Heft / Issue:
48
Seitenangaben Beitrag:
33384-91
Sprache:
eng
Volltext / DOI:
doi:10.1074/jbc.M109.021659
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19808671
Print-ISSN:
0021-9258
TUM Einrichtung:
Institut für Virologie
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