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Titel:

Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Andersen, CA; Rosenkrands, I; Olsen, AW; Nordly, P; Christensen, D; Lang, R; Kirschning, C; Gomes, JM; Bhowruth, V; Minnikin, DE; Besra, GS; Follmann, F; Andersen, P; Agger, EM
Abstract:
The immunostimulatory activity of lipids associated with the mycobacterial cell wall has been recognized for several decades and exploited in a large variety of different adjuvant preparations. Previously, we have shown that a mycobacterial lipid extract from Mycobacterium bovis bacillus Calmette-Guérin delivered in cationic liposomes was a particular efficient Th1-inducing adjuvant formulation effective against tuberculosis. Herein, we have dissected the adjuvant activity of the bacillus Calmet...     »
Zeitschriftentitel:
J Immunol
Jahr:
2009
Band / Volume:
183
Heft / Issue:
4
Seitenangaben Beitrag:
2294-302
Sprache:
eng
Volltext / DOI:
doi:10.4049/jimmunol.0804091
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19620310
Print-ISSN:
0022-1767
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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