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Document type:
journal article
Author(s):
Debela, M; Beaufort, N; Magdolen, V; Schechter, NM; Craik, CS; Schmitt, M; Bode, W; Goettig, P
Title:
Structures and specificity of the human kallikrein-related peptidases KLKs 4, 5, 6, and 7.
Abstract:
Abstract Human kallikrein-related peptidases (KLKs) are (chymo)-trypsin-like serine proteinases, which are expressed in a variety of tissues such as prostate, ovary, breast, testis, brain, or skin. While their physiological functions have been elucidated only partially, many of the KLKs appear to be useful prognostic cancer markers, showing distinct correlations between their expression levels and different stages of cancer. Recent advances in the purification of'new-type' recombinant KLKs allow...    »
Journal title abbreviation:
Biol Chem
Year:
2008
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18627297
Print-ISSN:
1431-6730
TUM Institution:
Frauenklinik und Poliklinik
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