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- Titel:
Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study).
- Dokumenttyp:
- Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Article
- Autor(en):
- Eberlein, B; Eicke, C; Reinhardt, HW; Ring, J
- Abstract:
- BACKGROUND: For long-term management of atopic eczema, the use of skin care creams is recommended, but effectiveness of this treatment is not well established. OBJECTIVE: The objective of this study was to yield data on the skin care properties of a cream with a unique lamellar matrix containing N-palmitoylethanolamine (PEA) and to assess quality-of-life variables in patients with mild to moderate atopic eczema. SETTING: In this multinational, multicentre, observational, non-controlled, prospective cohort study, patients between 2 and 70 years of age were enrolled. All patients were supplied with the study product sufficient for treatment over the entire study period. Outcome was followed in periods between 3 and 7 days and 4 and 6 weeks after study start. Data were gathered from doctor reports and patient self-assessments via patient questionnaires. RESULTS: Data from 2456 patients entered the database. The mean examination intervals were 6 days for the 3- to 7-day period and 38 days for the 4- to 6-week period. At study end, intensities of erythema, pruritus, excoriation, scaling, lichenification and dryness were significantly reduced with a combined score reduction of 58.6% in the entire population (57.7% in adults > 12 years and 60.5% in children
- Zeitschriftentitel:
- J Eur Acad Dermatol Venereol
- Jahr:
- 2008
- Band / Volume:
- 22
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 73-82
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1111/j.1468-3083.2007.02351.x
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/18181976
- Print-ISSN:
- 0926-9959
- TUM Einrichtung:
- Klinik und Poliklinik für Dermatologie und Allergologie
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