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Title:

Skin tests in the diagnosis of drug hypersensitivity reactions.

Document type:
Journal Article; Review; Review
Author(s):
Brockow, K; Romano, A
Abstract:
Adverse drug reactions (ADRs) are an area of concern for pharmaceutical drug development. Among these, drug hypersensitivity reactions are neither dose-dependent nor predictable, and affect only predisposed individuals. Clinical and immunological studies suggest that IgE-mediated (type I) and cell-mediated (type-IV) pathogenic mechanisms are involved in many immediate (i.e., occurring within 1 hour after the last drug administration) and non-immediate (i.e., occurring more than 1 hour after the...     »
Journal title abbreviation:
Curr Pharm Des
Year:
2008
Journal volume:
14
Journal issue:
27
Pages contribution:
2778-91
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18991697
Print-ISSN:
1381-6128
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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